The £14bn plan has been backed by majority 415 MPs with only 119 remaining unconvinced.
This vote sparks the process to begin applications for the project. If the green light is given construction could begin in 2021 with the new runway being completed in 2026.
The airport will now commence signing £150m worth of contracts which will create 200 new apprenticeships and 900 new jobs.
Heathrow will hold a second public consultation before officially submitting development consent order application to the Planning Inspectorate.
The government has pledged that the £14bn will be funded privately and that there will be no taxpayer input.
[Video source: https://www.youtube.com/watch?v=r-ips0uVHHs]